a rare hyperinflammatory syndrome detected in infected children

The children were relatively spared by the Covid-19 pandemic, most of their symptoms being mild, in the event of contamination. However, pediatricians have found a new hyperinflammatory syndrome “potentially fatal”, called “MIS-C”. This syndrome resembles Kawasaki disease, a condition that can appear in infants and children aged 1 to 8 years. It is characterized in particular by a prolonged fever, conjunctivitis and inflammation of the mucous membranes.

A collaborative study analyzed blood samples from 13 “MIS-C” patients: the latter were treated at Karolinska University Hospital in Stockholm, Sweden and at Bambino Gesù Children’s Hospital in Rome. These samples were then compared “with samples from 28 patients with Kawasaki disease collected from 2017 to 2018, before the appearance of the coronavirus“, details a newspaper article The Independent.

MIS-C: a “distinct” inflammatory disease

“Our research shows that MIS-C is truly an inflammatory disease distinct from Kawasaki disease, despite some common characteristics,” Petter Brodin explained. This specialist is a pediatrician and researcher in the Department of Women’s and Children’s Health at Karolinska Institutet, one of the main collaborators of the study in Sweden.

Petter Brodin explains that “hyperinflammation and cytokine production” in children with MIS-C is different from that seen “in adult patients with severe and acute coronavirus“, noting thatit is “urgent to better understand why a small minority of children infected with SARS-CoV-2 ”developed this pathology.

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