According to a study published in the journal Science Translational Medicine, the appendix acts as a reservoir of the lfa-synuclein protein, associated with that disease that affects memory. Therefore, the appendectomy reduces the chances of suffering from Parkinson's.
"Our results point to the appendix as a site of origin for Parkinson's and provide a way to design new treatment strategies that take advantage of the role of the gastrointestinal tract in the development of the disease," said lead author Viviane Labrie.
"Despite having a reputation for being largely unnecessary, the appendix actually plays an important role in our immune system, in regulating the composition of our intestinal bacteria and now, as our work demonstrates, in the disease of Parkinson ", explained the scientist.
The risk reduction for Parkinson's disease only became evident when the appendix and the alpha-synuclein it contained were removed early in life, years before the onset of the disease, suggesting that the appendix could participate in its onset. .
Removal of the appendix after the disease process began, however, had no effect on its progression.
More common. In a general population, people who had an appendectomy were 19% less likely to develop Parkinson's, which was magnified in people living in rural areas, with appendectomies that resulted in a 25% reduction in the risk of developing the disease .
The incidence of this disease is often higher in rural populations, a trend that has been associated with increased exposure to pesticides, the study found. .