ARTERIAL STIFFNESS: An excellent predictor of diabetes risk

According to the Centers for Disease Control and Prevention (CDC), more than 37 million people in the United States in 2019 had diabetes, with approximately 90-95% having type 2 diabetes. The prevalence of diabetes is on the rise across the the world, due to unhealthy lifestyles and an aging population. With a large type of consequences, cardiovascular diseases and events. Among other comorbidities.

Better detect patients at high risk of type 2 diabetes

This detection of people at high risk of diabetes has become a public health emergency, as early intervention can prevent the development of the disease and slow the rise in its prevalence in the general population, recalls the main author, Dr. Anxin Wang, a researcher at Tiantan Hospital in Beijing.

Arterial stiffness, predictive and major sign of type 2 diabetes: Previous studies have already shown that hypertension is a risk factor for type 2 diabetes. This new study reveals that arterial stiffness, a factor frequently correlated with high blood pressure, is also associated with resistance to insulin and type 2 diabetes.

HTA or arterial stiffness, what is the most predictive factor?

“Since people with high blood pressure or stiff blood pressure tend to have a higher risk of type 2 diabetes, we looked at which of these 2 factors was more predictive of future risk of type 2 diabetes.”

The study: analysis of data from 11,156 participants in the Kailuan study, a prospective study involving more than 100,000 people, taking into account their resting blood pressure and the measurement of arterial stiffness, reveals that:

  • over a 65-year follow-up, approximately 7% of participants developed type 2 diabetes;
  • vs participants with normal vascular function, participants with high arterial stiffness associated with high blood pressure have the highest risk of type 2 diabetes;
  • participants with normal blood pressure but arterial stiffness also have an increased risk of type 2 diabetes compared to the group with normal vascular function;
  • participants with high blood pressure but normal arterial stiffness had the lowest risk of type 2 diabetes;
  • the combination of hypertension and arterial stiffness is more frequent in men, and in older people, in the event of a higher BMI, higher heart rate and with smoking and excess alcohol;
  • finally, increased arterial stiffness is associated with higher fasting blood sugar and cholesterol levels.

Thus, people with high arterial stiffness have a higher risk of diabetes, whether or not they have high blood pressure. These results confirm that arterial stiffness may be a better predictor than blood pressure in detecting future risk of type 2 diabetes.

Many risk factors for type 2 diabetes are modifiable: the authors point out that opting for a healthy lifestyle promotes both good metabolic and cardiovascular results. However, this highlighting of the importance of arterial stiffness in the risk of type 2 diabetes improves our understanding of the correlation between cardiovascular disease and type 2 diabetes.