Covid-19: Dozens of studies confirm that people with blood type “O” are less contaminated

Around 40 studies now confirm that people with blood type O have a lower risk of contracting the coronavirus. It even gives ideas to French researchers.

A recent study carried out by Spanish doctors on just over 6,000 patients shows that people in the O + group seem better protected from Covid-19. Regardless of their age or gender, they tested positive less often than others. At the end of January, researchers from Inserm and the University of Nantes even wrote in the journal Virus “that a general consensus has emerged, according to which the O groups have a lower risk of the disease than the others. , between 10 and 33% less risk ”.

This does not mean that people with this blood type can overcome barrier gestures. Researchers relate the proportion of blood groups in a population to the pace of the epidemic. For example, South Korea has a good balance and has brought the virus under control quite well. On the other hand, in Manaus, Brazil where only one blood group is the majority, the epidemic has wreaked havoc. In fact, when the virus comes knocking on your body’s door, it is marked with the blood type of its previous host.

The O blood groups defend themselves better than the others, because they have natural antibodies A and B. While the A have only B and vice versa. On the other hand, if they are infected by someone from the same group O, then the virus can enter. It is therefore not a totem of immunity. In France, the population is rather balanced with 44% of group A, 42% of group O, 10% of B and 4% of AB.

The hypothesis of blood that clots less

This study was done before the arrival of the variants. But for Jacques Lependu, from Inserm and one of the authors of the study, if it is the same mechanism that is at work, it must work in the same way, as he verified with the Sars of 2003. But another hypothesis can also explain this better protection of the O groups, it is that their blood clots less, they thus avoid thromboses, vascular problems which are part of the complications of the coronavirus.

The researchers now want to test this biological mechanism in vitro to find evidence for what they are seeing in the epidemic numbers. One way to be able to find, they hope, better protection against the virus.


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