KATERYNA KON / SCIENCE PHOTO LIBRARY
Scientists have dismantled the cancer piece by piece and discovered its weak points in a possible scientific breakthrough.
In one of the largest studies of its kind, scientists stopped all genetic instructions within 30 types of cancer. They discovered 600 genetic genes, which could be targeted by drugs that would not harm healthy cells in the body.
At present, chemical treatments attack the whole body, leading to unwanted side effects, including hair loss, nausea and fatigue.
But the new results, described as "strong" by British cancer research, can lead to a free treatment of cumbersome effects.
"This is very important, because we are currently treating cancer through a targeted treatment of the entire patient's body, without specifically targeting cancer cells," said Dr. Fiona Behan, the study's co-author. "The information we uncovered in this study, Identified the main weaknesses of cancer cells, allowing scientists to develop drugs targeting them without harming healthy cells.
Scientists, led by the Wellcome Sanger Institute, have disabled about 20,000 genetic genes in more than 300 cancerous models in the laboratory.
They focused on common cancers, such as lung, colon and breast, as well as those requiring urgent treatments, such as the pancreas.
Scientists have found several thousand major genes, which are essential for the "flowering" of cancer.
The research team reduced the number to 600 of the most important genetic genes in the development of treatment. The results were published in the journal Nature.
The cancer, which has a wrong DNA pathway, appears to require the enzyme "helicase req" (WRN) to continue to grow, but if it can be targeted with drugs, cancer tumors can be eliminated.
WRN is found in about 15% of colon cancers and 28% of stomach cancers, but no drugs are targeted.
Another gene, "herceptin", found in breast cancer, which is already the target of some treatments, confirmed the results.
Source: Daily Mail