East Java Tribune – Tribunnews.com
Fatty food can make you mentally disturbed
Fatty Foods Not Only Make Your Body Fat, But It Can Also Cause Mental Disorders, How come?
Sajiansedap.com – The human body normally needs fat to support the system in the body.
But apparently not all types of fat have benefits for the body good.
Some can actually be dangerous, one of which is saturated fat.
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So far, we are always advised to limit fat consumption, to avoid obesity or obesity, but it turns out that too much fat accumulation can also cause mental disorders.
How could that be?
Are you curious?
Here is the full explanation for you.
Accumulating Fat Causes Mental Disorders
A group of researchers from the University of Glasgow in the United Kingdom and Gladstone Institutes, in San Francisco, CA, recently studied how eating foods high in saturated fat can make depression more likely, using a mouse model to do it.
The researchers – led by Prof. George Baillie, from the University of Glasgow – notes that this is a very important research topic, because depression related to obesity seems to occur through different mechanisms of depression in healthy individuals.
In their study paper, which appeared in the journal Translational Psychiatry, the research team explained that many people with obesity and depression, who doctors treat with ordinary antidepressants, do not see any benefit from treatment.
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At the same time, people with obesity and depression also don’t experience some of the side effects that people usually associate with these antidepressants, such as further weight gain.
“When compared to patients with normal weight, patients who are overweight and obese show response “which is substantially slower for antidepressant treatment, less improvement in neuroendocrinology and cognitive processes, and less weight-increase that is antidepressant-induced,” the researchers wrote.
So, what happens to the brains of people who are advantages weight or have obesity which makes them more susceptible to depression?
To get a basic idea, the research team conducted a preliminary study in a mouse model where scientists fed high-fat foods, which contained up to 60% saturated and unsaturated fats.
Mammalian brains, including humans, actually need certain fatty acids, such as omega-3s, to function properly.
The human body, in particular, cannot synthesize its own fatty acids, so they need to absorb these nutrients from food.
However, not all fatty acids are equally healthy, and excess fatty acids in the body can cause health problems.
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The researchers looked at how fatty acids accumulate in the brains of mice that eat high-fat foods, and whether these substances influence the mechanisms that bind scientists to mental health and behavioral changes consistent with depression.
Shortly thereafter, the team found that mice in their study experienced the entry of palmitic acid into an area of the brain known as the hypothalamus, which regulates the release of various hormones into the bloodstream.
Palmitic acid is a common saturated fatty acid that is present in a variety of foods and ingredients.
Including palm oil and olive oil, cheese, butter, margarine, and some meat products.
The article continues after the video below:
According to previous research, these fatty acids can explain the relationship between obesity and an increased risk of cardiovascular problems.
Through current research, researchers have discovered another role – it seems that high levels of palmitic acid in the hypothalamus alter the signaling pathways that researchers have linked to depressive characteristics.
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This pathway, known as cAMP / PKA, is involved in many metabolic processes, including dopamine signaling, which, in turn, contributes to the regulation of emotions.
So, at least in mice, researchers can confirm that absorption of certain dietary fats has a direct impact on the brain’s signaling pathway, which affects the development of depression.
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Article Has Been Published on intisari.grid.id with Title, Health Studies: Not Only Make Fat, Fatty Foods Can Also Cause Mental Disorders