The US Food and Drug Administration (FDA) announced Wednesday that severe genital infection has been reported in patients who have taken a particular class of diabetes medications.

The alert refers to a class of drugs called SGLT2 inhibitors, first approved in 2013 to lower blood sugar levels in adults with type 2 diabetes.

The US Department of Health has also called for this risk to be included in the labeling of medicines.

DELAWARE REPORTS THE FIRST RABYTOD SINCE 1941

FDA-approved SGLT2 inhibitors include Johnson & Johnson's Invokana, Eli Lilly & Co.'s Jardiance, and Bristol-Myers Squibb, Astra Zeneca Plc, Merck & Co and Pfizer Inc.

Companies have not responded immediately to Reuters request for comment.

Patients are at risk of infection known as Fournier gangrene, an extremely rare, but life-threatening bacterial infection of the tissue under the skin surrounding the genital area, the FDA said in a statement.

The bacteria usually get through a cut in the body and spread quickly. Diabetes is a risk factor for the development of Fournier gangrene.

DETROIT SCHOOLS SHUT OFF WATER OVER HIGH LEVEL LEAD, COPPER

The FDA said it identified 12 cases of Fournier gangrene – 7 in men and 5 in women – between March 2013 and May 2018.

One patient died while some required multiple disfiguring surgeries and developed complications, the agency said.

The infection developed within a few months after the patients had received a SGLT2 inhibitor and the drug was stopped in most cases, the FDA said.

LEAVE A REPLY

Please enter your comment!
Please enter your name here

This site uses Akismet to reduce spam. Learn how your comment data is processed.