Gene mutation found in monkeys and mice could serve as an antiviral to block HIV and Ebola

Discovery may have application in human treatments.

A team of North American researchers has discovered how a genetic mutation found in monkeys and mice interferes with the HIV and Ebola viruses, a finding that could have application in treatments in humans.

Led by scientists at the University of Utah and The Rockefeller University, the research has determined how the ‘retroCHMP3’ gene disrupts the ability of certain viruses to leave an infected cell, thus preventing them from reaching other cells.

“This was an unexpected finding. We were surprised to find that by slowing down cell biology a bit, we took the replication of a virus out of play,” said University of Utah geneticist Nels Elde and lead author of the study published today in the journal Cell .



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