Certain genetic factors can affect our body in a paradisiacal way. A team of scientists has identified 14 new genetic variations that have been linked to a higher body mass index (BMI) but can lower the risk of diabetes, lower blood pressure and lower the risk of heart disease.
Researchers believe that the place where excess fat is stored could be genetically determined – in the middle or around the liver.
This place is more important than the amount when it comes to insulin resistance and the risk of diabetes and other diseases.
"There are some genetic factors that increase obesity, but paradoxically reduce the risk of metabolism, and it has to do with where the fat is stored in the body," said Alex Blakemore, a professor at Brunel University London.
The results showed that people who carry these genetic factors store them safely under the skin with increasing weight gain and thus have less fat in their major organs such as the liver, pancreas and kidneys.
"It's better under the skin than the organs, especially the liver," Blakemore added.
For the study published in the journal Diabetes, the team examined more than 500,000 people between the ages of 37 and 73 years.
They used magnetic resonance imaging (MRI) on the waist of these individuals to compare where they stored extra fat, whether they showed signs of type 2 diabetes, heart attack, and stroke.
"There are many overweight or obese individuals who do not bear the anticipated metabolic disease risks associated with higher BMI," said Hanieh Yaghootkar of the University of Exeter in the UK.
"Meanwhile, some lean or normal-weight individuals develop diseases like type 2 diabetes," Yaghootkar said.
(This story was not edited by Devdiscourse staff and is automatically generated from a syndicated feed.)