(Photo d'illustration) A patient with cystic fibrosis developed cancer in France shortly after receiving a smoker's lungs, according to a study published in the journal Lung Cancer. – Eric Feferberg afp.com
A study published in the journal Lung Cancer warns about the risk of transplanting organs from smoking patients, after a patient with cystic fibrosis has developed
a cancer in France shortly after receiving in
transplant the lungs of a very regular nicotine consumer.
The patient was followed since childhood for cystic fibrosis. After a rapid deterioration of its respiratory functions, typical of cystic fibrosis, the doctors decided, in November 2015, to carry out a lung transplantation. In June 2017, the patient grafted, sick, is admitted in unit of thoracic oncology of the university hospital of Montpellier. Two months later, she died of lung cancer without any therapy being attempted.
Take more precautions
"According to the donor database, the transplanted lungs were taken from a 57-year-old woman who had been smoking a pack a day for 30 years," says the study, conducted by doctors at Montpellier University Hospital. She states that the examinations performed at the time of the donor's brain death revealed no abnormalities.
According to the study, the symptoms strongly recall those of cancer caused by smoking. "The short delay between lung transplantation and the appearance of the first radiological abnormality suggests that carcinogenesis began during the life of the donor," the authors of the work add. A cancer whose growth would have been greatly accelerated by the immunosuppressive treatments that the patient followed to avoid rejection of her new lungs. For Dr. Jean-Louis Pujol and his colleagues, "given the relatively long latency of lung cancer, we suggest that transplants from smoker (or recently arrested) donors be considered with caution."