A 39-year-old woman died of cancer after receiving a smoker's lungs. This patient from the University Hospital of Montpellier was followed since childhood for cystic fibrosis. In November 2015, while suffering from a "sudden decrease in her breathing capacity," she is grafted, reports an article from the journal Lung Cancer, quoted by Le Monde.The transplant came from a 57-year-old woman who had smoked the equivalent of 20 cigarettes a day for 30 years. Before the transplant, the examinations did not reveal any anomaly. Two years later, the patient suffers from respiratory insufficiency and fever. After a chest scan, the doctors discover several suspicious lung foci in both lungs. Two months later, she dies of lung cancer without any therapy can be attempted. Immunosuppressor accelerates cancer In their study, Prof. Jean-Louis Pujol and colleagues of the unit of thoracic oncology and of the medical imaging department at the Arnaud de Villeneuve Hospital (Montpellier) note that "the short delay between lung transplantation and the appearance of the first radiological anomaly suggests that carcinogenesis began during the life of the donor" . They add that the cancer of this patient has developed particularly fast because of its immunosuppressive treatment, which avoids the rejection of the transplant. The medical team recommends taking precautions in case of organ donation from patients. smokers for "active" (or recently quit) smoking transplant recipients to be considered with caution as the emergence of lung cancer in the recipient is triggered by immunosuppressive therapy ".


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