New best practice guidelines developed by the American Society for Radiation Oncology (ASTRO) have just been published in the Journal Practical Radiation Oncology. These evidence-based recommendations frame new advanced radiation therapy techniques to manage intact and resected brain metastases from non-hematologic solid tumors.
Radiation therapy is commonly used to treat brain metastases, prolong survival, and relieve headaches, dizziness, and other associated neurological problems. In order to reduce the cognitive deterioration most often caused by broad brain irradiation, techniques such as stereotactic radiosurgery, or even whole brain irradiation sparing the hippocampus, make it possible to limit exposure to healthy brain tissue.
If we add to this emerging systemic therapies, such as immunotherapy or new targeted therapy drugs, which can serve as alternatives or complements to radiotherapy and surgery, we see that the therapeutic arsenal, in this area has made significant progress.
It is to support these developments and sustain the quality of radiotherapy care that the American Society for Radiation Oncology (ASTRO) has updated its best practice recommendations for the treatment of brain metastases. These recommendations address patient selection, as well as techniques for planning and administering radiation therapy to manage intact or resected brain metastases. They also provide treatment algorithms for limited brain metastases and extensive brain metastases.
Bruno Benque with ASTRO