Nuclear medicine in the diagnosis of asymptomatic pulmonary embolism due to covid-19 – Prensa Libre

The coronavirus disease covid-19, which emerged in Wuhan, China in December 2019 and caused by SARS-CoV-2, in three months became a pandemic as declared by the World Health Organization on March 11 2020.

Chest computed tomography (CT) is of special relevance in the diagnosis of coronavirus disease, it allows to identify alterations early, being sensitive, this data is important in patients with high suspicion (clinical and analytical) and negative results of RT- PCR (Real Time Polymerase Chain Reaction), which is considered a standard reference test for diagnosis, but it achieves a false negative rate of up to 29% depending on the series.

The clinical serological manifestations (elevation of money “D”) and radiological published to date in clinical practice have shown a high rate of thromboembolic disease probably related to associated coagulopathy. Infection-induced endothelial cell dysfunction results in excess thrombin production and fibrinolysis blockage, leading to a hypercoagulable state, the severe hypoxia present in patients with this covid-19 disease can also stimulate thrombosis. The presence of occlusion and microthrombosis has been demonstrated, which is a limitation of the method and is histological findings of a series of lung autopsies in patients with covid-19.

Pulmonary angiography with multi-detector computed tomography is one of the imaging techniques of choice to rule out pulmonary thromboembolism, small filling defects in the distal arterial branches, of small caliber, can go unnoticed.

The perfusion ventilation study has been compared with covid_19 patients, money elevation “D” and the use of single photon emission tomography (SPECT-CT) that uses injecting small particles that are distributed in the small vessels and capillaries of the lung tissue that they detect micro-thrombi of the distal branches, of small caliber.

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Using the interpretation parameters of the European Association of Nuclear Medicine and molecular imaging. The final diagnosis was made by consensus by pulmonologists, radiologists, and nuclear physicians based on the laboratory and imaging results of both methods (SPECT-CT, pulmonary tomography angiography).

The various professionals who participated in this study and after the analysis of the results in patients who had confirmation of the presence of post-covid-19 pulmonary embolism after their statistical analysis concluded that SPECT-CT is more sensitive and specific in this compared diagnosis with anti-tomography.

Bernardo Coronado M.

The various professionals who participated in this study and after the analysis of the results in patients who had confirmation of the presence of post-covid-19 pulmonary embolism after their statistical analysis concluded that SPECT-CT is more sensitive and specific in this compared diagnosis with anti-tomography.