Risk of myocardial infarction if hemodialysis patient fractures

A domestic report reported that fractures in hemodialysis patients increase the risk of myocardial infarction.

The Korean Society of Nephrology examined the relationship between hemodialysis patients and the risk of fracture and myocardial infarction through data from the Health Insurance Review and Assessment Service.

As a result, 5,057 (13%) of 38,935 patients (11,379 patients with hemodialysis and 27,556 patients with chronic kidney disease) had fractures.

Of these, a total of 1,431 patients (3.7%) had acute myocardial infarction.

In particular, hemodialysis patients with vertebral fractures were at twice as likely to develop myocardial infarction compared to non-fractured groups.

The reason is due to various factors affecting vascular calcification and bone strength (hyperphosphatemia, elevated FGF-23, decreased vitamin D, hyperparathyroidism, etc.).

The research team analyzed that the factor is a common cause of the risk of fracture and myocardial infarction in hemodialysis patients, and that hypotension and ischemic injury that may occur during dialysis further increase the risk of myocardial infarction.

Professor Kwon Young-joo of Daegu Guro Hospital said, “In chronic kidney disease patients, more attention is required for bone health, including bone density, and it is necessary to monitor the occurrence of acute myocardial infarction in hemodialysis patients with fracture.” “It is an important research result that suggests the establishment of basic data for management and its association with cardiovascular disease.”

The study was published online in the journal OSTEOPOROSIS INTERNATIONAL.


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