This article is taken from the monthly Sciences et Avenir – La Recherche n°908, dated October 2022. To treat certain diseases (essentially genetic diseases where only one gene is affected), scientists have been developing powerful tools since the 1990s aimed at repairing or replacing faulty genes or organs. If it is a faulty gene responsible […]

Return of gene therapy: How to make the treatment safer

At the Wyss Institute for Biologically Inspired Engineering at Harvard University in Boston, Massachusetts, viral immunologist Ying Kai Chan is trying to develop safer AAV vectors. The risks increased when researchers used larger amounts of AAV, he told the conference: “I’m a big fan of reducing the dose.” But this may require the development of […]