The University of Glasgow received benefits worth up to £ 199 million from the slave trade, researchers said.
The university conducted a one-year study of thousands of donations made in the 18th and 19th centuries, and discovered that some were linked to the profits of the slave trade.
The establishment of a center for the study of slavery and commemoration on the campus in the name of the enslaved has now been decided by the university as part of a reparative justice program.
The study found 16 scholarships, foundations and estates that were donated between 1809 and 1937 with direct links to slavery gains.
Donations to the 1866-1880 campaign to build the current campus in Gilmorehill found that 23 people who gave money had financial ties to the New World slave trade.
Overall, it is estimated that the money received today has a value between 17 and 199 million pounds.
The Director of Glasgow University, Sir Anton Muscatelli, said: "This report was an important undertaking and a commitment to find out if the university has benefited from slavery in the past.
"Although the university never owned enslaved people or bartered for the goods they produced, it is now clear that we received considerable financial support from people whose wealth came from slavery.
"The University deeply regrets this connection with historical slavery, which clashes with our proud history of support for the abolition of both the slave trade and slavery."
He highlighted the university's historic anti-slavery activity, which included petitioning the parliament to abolish slavery, honoring emancipationist William Wilberforce, and training former slave James McCune Smith, who was the first African American to obtain a medical degree ,