LONDON (Reuters) – A tall genetic study shows that height makes one more likely to develop varicose veins or so-called varicose veins.
Varicose veins are swollen and twisted veins that can be seen directly below the skin, usually in the legs. More than 30 million people in the United States suffer from varicose veins.
Although this condition is often described as merely irritating to the cosmetic aspect, it can cause moderate pain and has been associated with a more serious side effect, ie deep vein thrombosis, ie blood clots in deep veins in the body.
In this study, the researchers analyzed the data of about 500,000 people who participated in the long-term study conducted by the British biobank, looking for features associated with the risk of varicose veins, which led to their height as a powerful risk factor.
The researchers then carried out a broad genetic survey of hundreds of thousands of people and identified 30 genes, many of which contribute to the growth of skeletons and blood vessels, indicating that height may be a direct cause of varicose veins.
"We do not yet know why height is such a powerful risk factor for varicose veins," said study author Nicholas Lipper of Stanford University in California.
"It may be a simple matter of blood flow and gravity," he said in an e-mail. "It takes a lot of pressure in their veins to grow up and expand."
"On the other hand, our strong genetic studies have shown that height is not only linked to the disease but appears to be caused by it, which is very different, because the genes that control human length may play a role in the structure and integrity of the veins," he said.
The study confirmed that surgery on the legs and the history of family disease and lack of movement and smoking and hormone therapy are all risk factors may also cause varicose veins .- (Reuters).


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