Meningococci can trigger sepsis in addition to meningitis. Vaccinations can protect

Vienna (OTS) – The World Sepsis Day on September 13 will help raise awareness of sepsis in public. The increased attention promotes the early detection of this serious disease and allows for early treatment. The colloquially often used term, blood poisoning 'is considered outdated, as it refers to pathogens and their toxins and thus the influence of the reaction of the organism in the pathogenesis is not sufficiently considered. (1) Sepsis is a systemic inflammatory response of the body to infection. These initial infections may be e.g. Pneumonia, intra-abdominal infections or urinary tract infections. (1) The pathogens subsequently spread in the body, which reacts with a systemic inflammatory reaction. A chain reaction of pro-inflammatory messengers and tissue damage can lead to severe sepsis or septic shock. In Europe, around half a million people suffer from sepsis every year, around 18,000 cases a year in Austria, and 7,500 die from it. (2) Causes of sepsis and protective optionsBesides viruses, fungi and parasites, bacteria also trigger sepsis. In children, it is primarily meningococci that cause invasive bacterial diseases such as sepsis and meningitis. While vaccines have long been available against the meningococcal serogroups A, C, W and Y, the meningococcal serogroup B remained the main pathogen for these diseases. After decades of research, since 2014, a vaccine against meningococcal B has been available in Austria since the age of 2. (3,4) GlaxoSmithKline – one of the world's leading research-intensive pharmaceutical and healthcare companies – is committed to improving people's quality of life. GSK manufactures vaccines for children and adults for a wide range of infectious diseases. GSK helps people lead a more active, healthier and longer life. For example, there is Since 2013, a unique worldwide partnership with the non-governmental organization "Save the Children", which aims to save the lives of one million children in developing countries. Further information can be found at and For the fifth time in a row, GSK is Number 1 in the Access to Medicines Index, has been a member of the Transparency International Austrian Chapter since 2013, and Austria's Leading Organization Austria. References: 1st Angus DC & van der Poll T.N Engl J Med. 2013 Aug 29; 369 (9): 840-512. The sepsis take the scare (retrieved on 30.08.2018) 3. Bryan P et al, Lancet Child Adolesc Health. 2018 Jun; 2 (6): 395-4034. Impfplan Österreich 2018References & Contact:
Dr. Philipp Günzl
Medical Advisor Vaccines
Tel. +43 664 8270098



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