Tuberculosis can be cured with shorter treatments, according to study

Tuberculosis can be cured with shorter treatments, according to study

London England.
Nearly half of the nearly 10 million patients with active TB (TB) diagnosed each year could be cured with treatments shorter than currently recommended, according to a study published today in "Nature Medicine." A new analysis from the University of California at San Francisco (UCSF) suggests that more precise therapies could be more effective when it comes to treating TB (a bacterial infection), which kills 1.3 million people worldwide each year. In the study – headed by Marjorie Imperial, a graduate student in Pharmaceutical Sciences at UCSF-, again analyzed the data obtained in three important tests that failed to demonstrate the efficacy of four-month treatments to treat this infection that attacks the lungs. of the UCSE stressed that the reason for the failure of these previous tests is that all patients were treated in the same way, without having account the severity of TB.In the new study, adds the research, when those patients were retrospectively stratified into three categories of the state of the disease: minimal, moderate and severe, the four-month treatment with drugs was highly effective for the 47 % of patients with minimal illness. However, the four months were not effective for patients who had moderate to severe TB. "Our study shows that a stratified medicine approach can be applied in a feasible way to achieve a shorter treatment for many patients with TB, "said Payam Nahid, of the School of Medicine of the aforementioned University of the United States." A unique (treatment) approach leads to a low treatment of patients with a serious condition of the disease, or excessive treatment for patients with less advanced disease, because they receive drugs that could cause harm, "Nahid added. TB has been treated with antibiotics since the discovery of streptomycin in 1943, although the bacteria that cause the disease quickly developed resistance to that antibiotic. In the seventies and eighties other treatments with rifampin were developed, but there was also a resistance to that antibiotic, remember the scientists, who highlight the danger of this situation since TB currently kills more people in the world than any other infectious disease. .

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