Metastatic Breast Cancer Shifts Toward Chronic Care Model As Survival Rates Rise

Why Many Doctors Now Believe Metastatic Breast Cancer Should Be Treated as a Manageable Chronic Condition

Managing long-term metastatic breast cancer treatment requires balancing continuous systemic therapies with monitoring cumulative side effects like neuropathy and fatigue. For decades, a diagnosis of metastatic breast cancer carried a grim prognosis, with survival often measured in months or a few short years. By 2025, that landscape has shifted. Improved surveillance, targeted drugs, and a … Read more

Toho University Researchers Find Rice Bran Compound Calms Gut Contractions

Researchers at Toho University discovered that ferulic acid, a natural polyphenol found in rice bran, reduces intestinal smooth muscle contractions by blocking voltage-dependent calcium channels. A naturally occurring compound found in whole grains and rice bran could soon offer a new way to target gastrointestinal motility disorders. Scientists at Toho University have demonstrated that ferulic … Read more

Excessive Daytime Napping Linked to Higher Mortality in Older Adults

Excessive daytime napping in older adults is associated with higher mortality rates, which researchers suggest may serve as a warning sign for underlying diseases, according to a study conducted by Harvard in partnership with Rush University Medical Center. Quantifying the Risk of Napping The research utilized data from the Rush Memory and Aging Project, which … Read more

Australia Projected to Fail Hepatitis Goals With $2.6 Billion Potential Cost

Australia is currently tracking to fail more than half of its targets to eliminate hepatitis by 2030. A new economic modelling report warns that failing to meet these goals could cost the nation $2.6 billion in avoidable healthcare and workforce expenses. The financial stakes of inaction are steep. According to a report commissioned by Hepatitis … Read more

Midlife Vitamin D Levels Linked to Lower Alzheimer’s Tau Proteins

Researchers found that healthy vitamin D levels in midlife are linked to reduced deposits of toxic tau protein, a known Alzheimer’s biomarker, as people age. The study, published in Neurology Open Access, tracked a sample of 793 adults, suggesting that midlife nutrient levels may offer a critical window for future brain health protection. Most research … Read more

Lipid Profile Blood Tests Help Detect High Cholesterol to Prevent Heart Attacks

Data from the latest Global Burden of Disease Study indicates that low-density lipoprotein (LDL) cholesterol, often called “bad” cholesterol, was responsible for 3.6 million deaths in 2023. This type of cholesterol is believed to cause a quarter of all stroke deaths and a third of all heart disease deaths globally. Detection and Risk Factors Because … Read more

University of Miami Researchers Develop Blood Panel to Predict ALS Onset

University of Miami researchers have identified a 19-protein blood panel that can predict when individuals with ALS-linked genetic variants will develop symptoms, often years in advance. Published in Nature Medicine, the findings allow scientists to estimate the time to symptom onset with an average error of about 18 months. For families carrying genes linked to … Read more

PediCAP Trial Finds Early Switch to Oral Antibiotics Safely Cuts Hospital Stays for Severe Pneumonia

Severe Pneumonia

Children hospitalized with severe pneumonia who transition from intravenous antibiotics to oral pills once they start improving can safely go home a day earlier than patients kept on full injectable courses, according to findings from the PediCAP trial published in CIDRAP. Researchers reported that children switched to oral treatments faced no greater risk of readmission … Read more

PROTEXI Cancer Vaccine Leverages COVID-19 Immunity to Fight Tumors

Researchers have developed a therapeutic cancer vaccine platform named PROTEXI that pairs tumor antigens with SARS-CoV-2 spike protein fragments, redirecting pre-existing COVID-19 immune memory to enhance T-cell responses against tumors. Preclinical results published in Nature Communications on July 27 showed slowed tumor growth in mice, with a first-in-human sarcoma trial planned. The global immune footprint … Read more

Climate Change Shifts Childhood Malaria Risks Across Africa

Rising global temperatures are redistributing the risk of childhood malaria across sub-Saharan Africa, creating areas of new risk in the eastern and southern parts of the continent while providing relief hotspots in western regions, according to a study published in Nature. The research investigates the historical and future impacts of climate change on childhood malaria … Read more