Methylation-Sensitive Cas9 Selectively Targets Tumor DNA

Beyond the Sequence: How Methylation-sensitive CRISPR is Redefining Precision Oncology For years, CRISPR-Cas9 has been hailed as a master of the genetic alphabet, capable of editing DNA with unprecedented accuracy. However, it has remained largely blind to the “punctuation” of the genome—the epigenetic markers that dictate whether a gene is turned on or off. The … Read more