D2HG & Tumors: Protein Changes Fuel Cancer Growth
The landscape of cancer research is shifting, moving beyond simply targeting the *production* of oncometabolites to understanding their direct and previously unappreciated impact on cellular machinery. A new study from Purdue University, published in Nature Chemistry, reveals that the cancer-associated metabolite D-2-hydroxyglutarate (D2HG) doesn’t just interfere with existing cellular processes – it directly *modifies* proteins, … Read more