Scientists Flip Immune System “Switch,” Uncover Surprising Path To Stop Gut Inflammation

The Weill Cornell Mechanism for Immune Tolerance

Researchers at Weill Cornell Medicine identified a mechanism to prevent chronic intestinal inflammation in a study published April 24 in the Journal of Experimental Medicine. The team discovered that blocking a specific immune signal, previously thought to be necessary for tolerance, actually reduced inflammation in preclinical models, offering new potential strategies for treating inflammatory bowel … Read more

Vitamin D & IBD: Gut Bacteria, Immunity & Response

The persistent challenge of inflammatory bowel disease (IBD) – encompassing Crohn’s disease and ulcerative colitis – may have found an unexpected ally in a readily available supplement: Vitamin D. A new study from the Mayo Clinic, published in Cell Reports Medicine, suggests Vitamin D isn’t just about bone health; it actively reshapes the immune system’s … Read more

Genomic Risk & Disease: Predicting Severity | Forecasts

For the 60,000 Danes living with chronic inflammatory bowel disease (IBD), and the millions more worldwide, the uncertainty surrounding disease progression is a constant burden. Beyond the physical discomfort – which can range from mild inconvenience to debilitating pain and the need for surgery – lies the anxiety of not knowing what the future holds. … Read more