Manly are set to unleash another Trbojevic brother in place of a key back-rower who has been cut from the side.
But the Sea Eagles have also been dealt a cruel injury blow.
Newcastle will be without Kalyn Ponga with the star fullback suffering an injury setback, while another key spine player has been ruled out.
Read on for all the latest NRL team news in Late Mail.
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Newcastle Knights vs Manly Sea Eagles at McDonald Jones Stadium, 4.05pm
Knights: 18. Tex Hoy 2. Starford To’a 3. Enari Tuala 4. Bradman Best 5. Brayden Musgrove 14. Connor Watson 7. Phoenix Crossland 8. David Klemmer 9. Jayden Brailey 10. Daniel Saifiti 11. Tyson Frizell 12. Lachlan Fitzgibbon 13. Mitchell Barnett 15. Jacob Saifiti 16. Sauaso Sue 17. Brodie Jones 19. Josh King 18th man: 20. Simi Sasagi
Players cut: 1. Kalyn Ponga 6. Kurt Mann 21. Jack Johns
Late Mail: Kalyn Ponga is out with a groin issue meaning Tex Today comes into the 17. Kurt Mann has been cut from the side and Connor Watson slots into the halves.
Sea Eagles: 1. Tom Trbojevic 2. Jason Saab 3. Brad Parker 4. Morgan Harper 5. Reuben Garrick 19. Tevita Funa 7. Daly Cherry-Evans 8. Taniela Paseka 9. Lachlan Croker 10. Martin Taupau 11. Karl Lawton 12. Sean Keppie 13. Jake Trbojevic 15. Moses Suli 16. Zac Saddler 17. Toafofoa Sipley 18. Ben Trbojevic 18th man: 20. Christian Tuipulotu
Players cut: 6. Josh Schuster 14. Curtis Sironen 21. Jorge Taufua
Late Mail: Ben Trbojevic — the younger brother of Tom and Jake — will make his NRL debut. Trbojevic, a second-rower, replaces Curtis Sironen who was scratched from the side 24 hours out from kick-off after not overcoming a knee injury in time for the clash. Trbojevic started the year in Jersey Flegg before progressing into NSW Cup. He’s had mixed performances for feeder club Blacktown Workers and was dropped back to Flegg at one stage. But Trbojevic returned to NSW Cup last weekend and had his best game of the year, which was enough to convince Des Hasler he’s ready for his opportunity in the top grade. Meanwhile, Josh Schuster has been ruled out after picking up a hamstring injury at training. Avoid Funa replaces him at five-eighth.
Referee: Ben Cummins