opioid

Opioid Agonists & GPCRs: New Biology, Better Pain Relief

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The relentless search for safer pain relief has taken a significant step forward, potentially offering a path to opioids that effectively manage pain *without* the deadly side effects of respiratory depression. Researchers at the University of South Florida have identified a compound, muzepan1, that interacts with opioid receptors in a novel way, hinting at a … Read more

Trump Declares Fentanyl a Weapon of Mass Destruction

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The Weaponization of Pharmaceuticals: How Fentanyl’s Designation Signals a New Era of National Security Threats Over 90,000 Americans died from opioid-related overdoses in 2023, a staggering figure that prompted a dramatic move by the Trump administration: classifying fentanyl as a weapon of mass destruction. But this isn’t simply a response to a public health crisis; … Read more

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