Tumour immunology

Pembrolizumab & Olaparib: Pancreatic Cancer Trial Results

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Promising New Treatment Approach for Metastatic Pancreatic Cancer Identified In a significant development for patients battling advanced pancreatic cancer, early results from the phase 2 POLAR trial suggest a novel, biomarker-driven treatment strategy is yielding encouraging responses. The approach focuses on identifying patients with metastatic pancreatic cancer who exhibit homologous repair deficiency and possess immune … Read more

mRNA Vaccines: Durable T Cell Response in TNBC

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The promise of personalized cancer vaccines took a significant step forward this week, with long-term follow-up data from a Phase 1 trial demonstrating sustained immune responses and, crucially, a lack of significant late-onset toxicity. While still early days, the results, published in Nature Medicine, bolster the case for individualized neoantigen vaccines as a potential treatment … Read more

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