Eli Lilly Invests $100 Million in Inflammation Drug Rights from CSL In a significant move signaling heightened competition within the burgeoning field of inflammation-targeted therapies, Eli Lilly and Company has secured rights to develop and commercialize clazakizumab, an IL-6-blocking antibody, from CSL Limited for $100 million upfront. This strategic acquisition positions Lilly to challenge established … Read more
Maternal Immune Dynamics: A New Frontier in Therapeutic Development A groundbreaking understanding of the complex interplay within a mother’s immune system is emerging, potentially unlocking novel therapies for a range of conditions. This isn’t simply about immunity to infection; it’s about a carefully orchestrated “split personality” that protects both mother and developing child, and whose … Read more
The relentless search for the root causes of multiple sclerosis (MS) has taken a significant turn, with new research from UCSF pointing to a potentially crucial role for the Epstein-Barr virus (EBV) and a specific type of immune cell. This isn’t simply confirming EBV’s presence – long known to be nearly universal in MS patients … Read more
Long COVID’s Hidden Drivers: The Emerging Role of Persistent Infections and Brainstem Dysfunction Over 65 million people worldwide are estimated to be living with Long COVID, a debilitating condition characterized by a bewildering array of symptoms that can persist for months, even years, after the initial infection. While the initial focus was on viral persistence, … Read more
The Immune System Reset: mRNA Therapies Poised to Rewrite the Rules of Aging Nearly 80% of all deaths globally are attributable to age-related conditions, many of which stem from a weakening immune system – a phenomenon known as immunosenescence. But what if we could not just treat the symptoms of an aging immune system, but … Read more
For decades, the paradoxical behavior of regulatory T cells (Tregs) in colorectal cancer has baffled researchers. While Tregs typically suppress the immune system, allowing tumors to thrive, a high concentration of these cells in colorectal cancer has consistently correlated with *better* patient outcomes. Now, a groundbreaking study from Memorial Sloan Kettering Cancer Center (MSK) has … Read more