Wolverhampton – Tottenham withstood mounting injury problems and a spirited Wolves fightback to claim a tense 3-2 victory at Molineux on Saturday.
Mousa Dembele and a shaky Premier League debut by Juan Foyth, Tottenham manager Mauricio Pochettino saw his side almost to throw away a 3-0 lead.
Yet goals from Erik Lamela, Lucas Moura and Harry Kane inside the first 61 minutes of Wolves setting up a grandstand finale.
Sanchez rested on the bench and Dele Alli left at home as the manager tried to manage his stretched resources ahead of next week's crucial Champions League tie against PSV Eindhoven.
Arsenal into fourth place in the Premier League.
It took just six minutes for Pochettino's injury worries to escalate when Belgian midfielder Dembele went down the ball.
He was helped on the edge of the pitch before being lifted on a stretcher and wheeled down the tunnel.
He was replaced in a change that forced a reshuffle, with Moussa Sissoko moving to his less favored holding midfield role.
Dembele joins knee injury victim Victor Wanyama on the sidelines along with Eric Dier, who is nursing a thigh problem, to leave young prospect Harry Winks as the only specialist central midfielder at Pochettino's disposal.
With 18-year-old Oliver Skipp among the substitutes for Tottenham and seemingly the next man in line for a midfield berth, Winks finds himself as a key figure for his club as he looks to push his claims for his next internationals later this month ,
Alli, who established a player who was suffering from a possible recurrence of a hamstring injury, could still be forced into action in a deeper-lying midfield role.
After a disjointed opening from both teams, Spurs scored twice in three minutes to turn the match decisively into their favor.
First, on 27 minutes, Lamela produced Touches of real quality to hold two defenders, play a clever one-two with Son and fire a crisp, low finish past Rui Patricio in Wolves' goal.
Then some poor defending from the hosts contributed to the visitors second in the 29th minute.
Moura, giving the winger a free, far-post header from Kieran Trippier's right-wing cross. Matt Doherty and Ryan Bennett both failed to pick up.
When Kane made it 3-0 on 61 minutes, forcing home a rebound after Patricio had parried his initial shot.
But Wolves set up a grandstand finish with two penalties, both conceded by debutant Foyth.
First the young Tottenham defender fouled Raul Jimenez, with Ruben Neves converting from the 68th minute spot.
When Foyth tripped Jonny in the 79th minute, it was Jimenez who scored the spot kick to leave Spurs sweating before their win was finally sealed.